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Three different tests: Tendon outgrowth , how many cells grow out from a piece of tendon in the dish Wound healing assay , cells are grown as a monolayer, you make a “scratch” in it and observe how quickly it closes Cell survival , you add peroxide (oxidative stress, which normally kills cells) and observe how many survive What they found: Tenocytes grew faster and in a dose-dependent curve (the more BPC-157, the more growth) The “scratch” closed 1.8× faster at 1 µg/ml BPC-157 Under oxidative stress, 22 % of cells survived without BPC-157, but 67 % with BPC-157 When they blocked the FAK enzyme, the effect disappeared → mechanism confirmed Why it matters: This is not just a “systemic effect via blood”, BPC-157 directly modifies the biology of an individual cell
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This individualized approach is particularly important when treating complex conditions like knee pain, where multiple factors may contribute to a patient’s discomfort
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