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In patients in deep coma, recovery often follows a stepwise pattern: first, return of basic vital brainstem functions such as spontaneous breathing, coughing, swallowing, and stabilization of blood pressure then defensive movements of the limbs (for example withdrawing from pain) later, recovery of functions such as eye opening and purposeful limb movements

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The significance of the differences between groups was assessed using a one-way ANOVA for repeated measures and Tukey’s post hoc multiple comparisons test