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The downstream effects of the two enzymes are opposite: ACE activity leads to vasoconstriction, oxidative stress, inflammation and apoptosis, whereas ACE2 causes vasodilatation, angiogenesis and anti-inflammatory, anti-oxidative and anti-apoptotic effects [1]
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10.1016/j.micpath.2022.105824 208 TiyaboonchaiW.RodleangI.OunaroonA
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