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The transplantation of IL-10-expressing MSCs into the medial cortex of the frontal lobe after rat brain injury has shown that MSCs provide a favorable microenvironment that promotes the polarization of macrophages from a proinflammatory phenotype (CD86) to an anti-inflammatory phenotype (CD163), resulting in immunomodulatory effects 56
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[DOI] [PubMed] [Google Scholar] 208.Tieppo C.A., Ferreira F.S., Sassatani A.S., Felicio L.F., Nasello A.G
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