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They have been attributed several functions to the microbiota related to the regulation of intestinal permeability, including the control of the proliferation of pathogenic bacteria, the stimulation of the immune system, the production of short-chain fatty acids, which modulate the host immune system and serve as a carbon source for colonocytes, and fermentation of amino acids and glucosaccharides [59]

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In published research, KPV enters cells and blocks NF-κB, a central switch in the inflammatory cascade, and shows anti-inflammatory activity in models of inflammatory bowel disease