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In contrast, the Delta variant also carries a L452R mutation in the receptor binding site which appears to increase the interaction between RBD and the ACE-2 and infectivity ( Our study has some limitations, including the lack of in-vivo studies and the exact mechanism of inhibiting ACE2 enzymatic activity
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Patients with increased circulating glucocorticoids often develop features of the metabolic syndrome, including central obesity, insulin resistance, hypertension, and dyslipidemia
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