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Affiliation: 1 Department of Translational Biomedicine and Neuroscience – DiBraiN, University of Bari “Aldo Moro”, 70124 Bari, Italy 2 MIRROR-Medical Institute of Regeneration and Repairing and Organ Replacement, Interdepartmental Center, University of Bari “Aldo Moro”, 70124 Bari, Italy 3 School of Dentistry, University of Dundee, DD1 4HN Dundee, United Kingdom 4 Department of Health and Life Sciences, De Montfort University, LE1 9BH Leicester, United Kingdom Email: [email protected] ORCID: Affiliation: 5 Department of Oral and Maxillo-Facial Science, University of Rome “Sapienza”, 00195 Rome, Italy ORCID: Affiliation: 6 Stem Cells and Medical Genetics Units, Biomedical Section, Tecnologica Research Institute and Marrelli Health, 88900 Crotone, Italy ORCID: Affiliation: 7 Department of Diagnostics and Public Health, University of Verona, 37100 Verona, Italy ORCID: Affiliation: 8 Department of Mechanics, Mathematics and Management, Polytechnic University of Bari, 70125 Bari, Italy ORCID: Affiliation: 6 Stem Cells and Medical Genetics Units, Biomedical Section, Tecnologica Research Institute and Marrelli Health, 88900 Crotone, Italy ORCID: Affiliation: 6 Stem Cells and Medical Genetics Units, Biomedical Section, Tecnologica Research Institute and Marrelli Health, 88900 Crotone, Italy ORCID: Explor Immunol

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The WRAIR projectile concussive impact model of mild traumatic brain injury: Re-design, testing and preclinical validation