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It was demonstrated that Cockayne syndrome (CS) complementation group A (CSA) protein, a DNA excision repair protein involved in the TC-NER sub-pathway, is required for the removal of 5′S-cdA adducts in DNA from primary skin cells (D'Errico et al., 2000)

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Using it for a multi-dose vial is asking for bacterial growth in a protein-rich solution

A few comments also mentioned undesirable aftereffects