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As additional proof, there is brain swelling in all rats not given therapy (Figure 5), increased intracranial (superior sagittal sinus) hypertension, and increased volume (associated with considerable brain injuries) (Figure 4) that BPC 157 administration rapidly counteracted, inducing a considerable decrease toward normal brain presentation (Figure 5) and negative pressure values (Table 1)
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Additionally, it has been documented that NNMT knockdown significantly mitigated both body weight and adiposity in female mice subjected to a Western diet, characterized by a composition of 47% kcal of fat and 34% kcal of carbohydrate (Brachs et al., 2019)
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