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[6] [8] Estradiol cypionate is contraindicated during pregnancy because exogenous estrogen has no therapeutic role in gestation and in utero exposure could theoretically disturb fetal endocrine development or contribute to structural anomalies, although robust human teratogenicity data are limited

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We discussed that without appropriate adjustments, ACOs caring for these populations may face financial penalties even if they succeed in improving access to high-value care during their agreement periods