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(89) in animal models confirmed that SIN attenuates inflammation by inhibiting both NF-κB and MAPK signaling pathways, leading to the downregulation of pro-inflammatory cytokines, such as IL-6 and TNF- α

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The proton nuclear magnetic resonance ( 1 H NMR, 400 MHz, D 2 O) spectra exhibited signals at δH 2.21 (quartet, 2H, H-3), 2.59 (triplet of doublets, 2H, H-4), 2.98 (doublet of doublets, 2H, CH 2 S), 3.86 (triplet, 1H, H-2), 4.02 (singlet, 2H, H-10), and 4.60 (triplet, 1H, H-7)