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The model was first fitted to the “training concentrations” (37.5 and 25 µM doxorubicin), and then used to simulate the “test concentrations” (50, 12.5 and 10 µM doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin

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It also mitigates the inflammatory response, leading to a decrease in the formation of reactive oxygen species (ROS) [85]

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