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While many individuals report a more radiant, brighter look after a series of glutathione IV treatments, it does not guarantee permanent or dramatic skin lightening

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25, 38 As aberrations in the TP53 gene and t(4:14) translocations are seen in ∼15% of patients 49 and correlated with short progression-free survival and resistance to alkylating agents at relapse, 50 the ability of BSO to sensitize MM cells with this phenotype suggests that BSO+L-PAM may have clinical activity in the most aggressive forms of MM