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Furthermore, TGF-β activates Smad signaling and can enhance the expression of DNA methyltransferases (DNMTs), leading to locus-specific modifications in DNA methylation that influence the expression of Treg-relevant genes (Ohkura and Sakaguchi, 2020)
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doi: 10.1016/J.JFF.2018.01.014 [DOI] [PMC free article] [PubMed] [Google Scholar] 126
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