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Some microbes, for example, use NADP + cofactor instead of NAD + (Fazel et al., a enzymes have also been identified in some microbes, such as the α-proteobacteria Zymomonas mobilis and Phenylobacterium immobile (Mayer et al., a , the legume family additionally possesses prephenate-specific TyrA p enzymes (Gamborg and Keeley, p in legumes combined with structural analyses, a single acidic residue in the active site, Asp222, was recently shown to confer arogenate substrate specificity of plant TyrAs by directly interacting with the side chain amine of arogenate substrate (Schenck et al., 1)

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