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Glycine supplementation can partially restore oxidative stress-associated glutathione deficiency in ageing cats | British Journal of Nutrition | Cambridge Core

Primary mouse peritoneal macrophages, mouse macrophage-like RAW 264.7 cells, and human monocytic THP-1 cells were transfected with GSTP encoding expression vector (pcDNA3.1-Flag-GSTP) or empty vector (pcDNA3.1), followed by stimulation of LPS (500 ng/ml) for 18 h, and the levels of HMGB1 in the culture medium were determined by ELISA

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Current research suggests that safety may depend on formulation, dosage, route of administration, and study design