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The current understanding of BPC-157 is derived almost entirely from in-vitro studies and controlled laboratory research models, and any findings should not be extrapolated to clinical, therapeutic, or veterinary applications

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Notably, these studies found that simple endothelial cell cultures did not show the same angiogenic response, suggesting that BPC-157 may act as a context-dependent regulator of vascular signaling rather than a direct angiogenic stimulus