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On the other hand, GSTP-knocked out colon cancer cell HCT116 has been reported to display proliferation impairment, with doubling time increased to 5 times that of normal cells due to oxidative stress state under the growth-limiting condition 45
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[C] The absence of methionine and cysteine residues means that the common oxidative degradation pathways affecting many peptides (+16 Da mass shift for methionine oxidation) do not apply to BPC-157
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