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Combination therapy The scientific rationale for combining 5ARIs and α 1 -AR antagonists is based on their different and complementary modes of action, that help in managing static and dynamic component responsible for of an enlarged prostate gland and symptoms of LUTS
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The TGA’s scheduling-decision record states that AOD-9604 was initially developed as an anti-obesity drug but that the programme was discontinued in 2007 because the clinical trials did not show a meaningful weight-loss outcome across the trial population
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