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Its antiβinflammatory effects are mediated through suppression of microglial and astrocytic activation, reduced release of proβinflammatory cytokines such as ILβ1Ξ² and TNFβΞ±, and inhibition of NFβΞΊB signaling, all of which help mitigate the chronic neuroinflammation implicated in AD progression (Capiralla et al
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After ingestion, vitamin B12 is released by undergoing proteolytic breakdown of its carrier proteins present in food at acidic pH of the stomach
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