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A randomized, placebo-controlled, double-blind, cross-over design clinical trial on EGCG in Italy (clinicaltrials.gov identifier: NCT00476138) reported that POAG patients who received oral EGCG treatment (200 mg/day) for 3 months in addition to standard IOP-lowering therapy showed increases in the amplitude of pattern-evoked electroretinograms as compared to the baseline values or to the patients who received the placebo treatment [126]
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The side effect profile does not include increased infection susceptibility at the rates seen with true immunosuppressants
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