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However, the elderly adults (mean age of 84) included in the study did show elevated T cell exhaustion markers following the third and fourth shots.[ref] Another study in cancer patients showed that some patients had a good response to the Covid booster, while approximately 30% of the cancer patients showed increased numbers of exhausted T cells after the third shot.[ref] ME/CFS and T cell exhaustion: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease that causes post-exertional malaise, cognitive changes, pain, flu-like symptoms, orthostatic intolerance, and fatigue
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