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Among these, the GA-derived AGEs (GA-AGEs) directly exerted toxicity on cells and are referred to as toxic AGEs (TAGEs) [13]

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As a medication, we applied BPC 157 (10 μg/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg) alone and/or combined, intravenously, immediately after intravenous heparin administration, while controls received simultaneously an equivolume of saline (0.5 ml/kg intravenously)