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Neuroprotection against Aminochrome Neurotoxicity: Glutathione Transferase M2-2 and DT-Diaphorase
Importantly, the stimulation of these pathways has been linked to glial hemichannel/pannexon activation under different pathological conditions, including amyloid β treatment (Gajardo-Gómez et al., 2017), prenatal inflammation (Orellana et al., 2015), spinal cord injury (Garré et al., 2016), high cholesterol diet (Orellana et al., 2014b), AD (Yi et al., 2016), and Niemann-Pick type C disease (Sáez et al., 2013)
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