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In the acute phase of SARS-CoV infection, there is erosion of the epithelial cells that line the airways and accumulation of debris and particles that obstruct the regular breathing pattern [28,29] There is also a risk of progression to more severe complications such as acute lung injury (ALI) and the subsequent Acute Respiratory Distress Syndrome (ARDS), which cover alveolar damage [27]

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Specifically, researchers want to ensure that compounds promoting rapid cell growth and new blood vessel formation do not inadvertently accelerate the growth of harmful, abnormal cells