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Figure 2 2.1.3 Iron metabolism and ferroptosis Iron is an essential trace element in the human body, playing multiple important biological roles, including inducing ATP production, participating in DNA and hemoglobin synthesis, and many other physiological activities ( Fe 3+ ions are reduced to Fe 2+ ions and then transported and stored in the cellular iron pool, while excess Fe 2+ ions are stored in ferritin (46)
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