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Weibel–Palade bodies (WPBs) are endothelial-specific organelles that contain molecules involved in the regulatory functions of the endothelium, such as ultra-large VWF multimers (proaggregating), P-selectin (proinflammatory) or Endothelin-1 (vasoconstricting)
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In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression
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