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This pathway is regulated by two key enzymes, CBS and CSE, furthermore, these two enzymes can also use cysteine as a substrate and are dependent on pyridoxal-5’-phosphate to produce dihydrogen sulfide as shown in the Figure 1
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Specifically, the infected tissue stromal, epithelial, or mucosal cells upregulate MMP expression and secretion in the presence of secretory microbial antigens [ e.g
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