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When we cultured Gclc- deficient iTregs or 4-OHT-inducible Gclc -deficient iTregs without serine, pS6 was reduced to control levels (Figure 5E) while FoxP3 was increased (Figure 5F)

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Although it is well-accepted that tight junctions are crucial for the maintenance of barrier integrity, the exact function of the individual tight junction proteins remain elusive