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In the Xenopus oocyte expression system, examination of rKOR regulation on the activation of potassium channels revealed that over-expression of GRK3 or 5 alone did not promote a significant desensitization which requires both GRK and arrestin 3 (Appleyard et al., 1999)
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RSPO2, specifically expressed in TSPCs, promotes tendon healing via the NF‐kB signaling pathway induced by either inflammation or mechanical loading, and inhibits heterotopic ossification, thereby maintaining tendon homeostasis [70]
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