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Importantly, hyperinsulinemia can occur before the onset of blood glucose dysregulation or elevations in blood glucose levels , implying that insulin resistance can exist before the onset of abnormalities seen in HbA1c or CGM

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doi: 10.1016/j.jcis.2020.07.056 [DOI] [PubMed] [Google Scholar] 79.Juang V, Chang CH, Wang CS, et al