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Changes in the prevalence of specific hemoglobinopathy and hemolytic anemia subtypes from 2011 to 2021 also demonstrated significant associations with PAH incidence
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for instance, the Na + /H + exchanger isoform 1 is markedly increased in hypertensive SHRs after ischemia and may be involved in BBB breakdown and brain edema development (Hom et al., 2007)
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