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during exercise-induced stress, pyruvate non-oxidative metabolism increases disproportionately, and the magnitude of blood lactate elevation is greater than that observed in healthy individuals, which suggests insufficient oxidative reserve of the tricarboxylic acid (TCA) cycle that fails to meet the metabolic demands under stress conditions
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Once transported across the plasma membrane, glucose is metabolically processed via three distinct pathways: glycolysis, the PPP, and the TCA cycle
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