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Electrophoreses and Lab-on chip analyses have revealed that purified anti-DNA antibodies from the sera of patients with SLE express electrophoretic patterns that differ from normal controls and vary between individual SLE patients
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Other preclinical work probed neuroendocrine signaling: DSIP has been described as modulating somatostatin release through a dopaminergic pathway in animal tissue, and several groups examined possible interactions with adrenergic transmission and with hormonal axes governing corticosteroid output
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