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The GSH/SLC7A11/GPx4 axis is the most important defense axis of ferroptosis, and SLC7A11, as the upstream of the ferroptosis pathway, serves as the raw material for the synthesis of GSH through the uptake of cystine, whereas GSH, through the action of GPx4, is able to reduce lipid peroxides on the plasma membrane to lipids and alcohols, thus protecting cells from ferroptosis [7,8]

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There's a whole category of things there we're not going to talk about today, although we might touch on a bit