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In particular, the subcellular compartmentation of NRF2 is dependent on the concentration of cytosolic free GSH (which promotes NRF2 dissociation from KEAP1) and nuclear TRX1 (which promotes NRF2-DNA binding) thereby contributing to the control of transcriptional regulation mediated by NRF2/ARE [133]
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Nat Catal 6 , 927–938 (2023)
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